The Free Exercise Clause prohibits the government from interfering with religion:

A law which unintentionally interferes with the free exercise of some religion will survive a Free Exercise Clause claim:

Southernstate law requires that all persons operating vehicles traveling public roadways attend a state driving course and pass a test. While this does not apply for self-powered vehicles, such as bicycles, it applies to all others. The course includes a mandatory driving portion during which students learn emergency handling in cars provided by the course operators. When the law is passed the Amish community protests, arguing that their horse-drawn carriages should be exempt and that requiring them to attend the course and operate the motor-vehicle conflicts with their religious beliefs. What is the likely result?

The Marijuana Ministry is a group holding itself out as a religion whose deity takes the form of marijuana plants. According to its founder, Chris Flaps, "we smoke marijuana to become closer to our god and to remind ourselves of her sweetness." After being arrested for possession, use, and distribution of marijuana, the Ministry's founder defends himself by appeal to the Free Exercise Clause and demands that his "church" be granted a limited exemption to the law of general applicability criminalizing marijuana. What is the likely result?